microbiome

Developing a range of products to modify the human
microbiome and bring specific health benefits

About the microbiome

The human digestive tract contains a complex and diverse ecosystem of trillions of bacteria.  Recently, advances in molecular and analytical techniques (metagenomics, metabolomics) have permitted identification and quantitation of species and strains of bacteria that inhabit the gastrointestinal tract, their metabolic activity, and interactions with the human host. These studies have provided greater insight into the role of gut and their metabolites in health and disease.

OptiBiotix has established a pipeline of microbiome modulators and which have a role in metabolic, skin and potentially into cognitive health (e.g stress, anxiety).

An understanding of the microbiome

Following a $3bn investment in the Human Genome project, the first draft of human genome was completed in 2003 by the Genome Bioinformatics Group at the University of California. This was widely heralded as a breakthrough event in understanding the treatment of a wide range of diseases, but to date is yet to deliver the expected transformation.

The human microbiome Project was launched in 2008, and with an initial budget of $115m, the first results were published in 2012. The importance of the role of the microbiome and the understanding of the interaction between human and bacterial cells is increasingly rapidly.

Information about the human microbiome

  • The human microbiome is made up of more than 100 trillion bacteria, fungi and viruses.
  • It is estimated that the average person has 10x more microbial cells than human cells
  • The interaction between the human and microbial cells is critical to sustained good health
  • OptiBiotix is applying a targeted microbiome modulation approach to promote a healthier microbial community by:-
    • Developing designer ingredients which can modify an individuals microbiome to improve health
    • Combining microbiome modulators with existing products such as probiotics to enhance the health benefit

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