Vasiliki Kachrimanidou in Probiota 2018 Barcelona: An in vitro evaluation of different carbohydrates on the selective fermentation of Lactobacillus rhamnosus ATCC 53103

The capacity of 53 different oligo and polysaccharides to specifically enhance the growth and activity of Lactobacillus rhamnosus ATCC 53103 (LR) in the gut was investigated using an pure and faecal batch cultures. Xylooligosaccharides and cellobiose mediated significant increases in LR concentrations. Significant increases were also observed in Bifidobacterium populations accompanied by a similar impact on acetate levels. No significant changes were noted on other faecal microbiome members.

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Steve O’Hara in Probiota 2017 Berlin: An assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum LPLDL® in adults with normal to mildly elevated cholesterol.

The University of Reading (UK) performed a double-blind, placebo-controlled, randomised human intervention trial with 50 volunteers, which were administered an encapsulated daily dose of 4x109cfu Lactobacillus plantarum LPLDL®. In this study, LPLDL®:

  • Was completely safe and well tolerated
  • Lowered total cholesterol by up to 36.7%
  • Lowered LDL cholesterol by up to 13.9%
  • Increased HDL cholesterol by up to 6.5%
  • Lowered systolic blood pressure by 5.1%

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Sofia Kolida in Probiota 2017 Berlin: Development of a synergistic synbiotic for Lactobacillus plantarum LPLDL® targeting cholesterol reduction

A reverse enzyme technology was used to synthesize LPGOS, galactooligosaccharides (GOS) that showed to selectively enhance the growth and activity of Lactobacillus plantarum LPLDL®. This was the first time true synergy is demonstrated for a synbiotic in faecal culture.

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Sofia Kolida in IPC (International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health) 2017 Budapest: Development of a Targeted Synergistic Synbiotic for Lactobacillus plantarum LPLDL®

A reverse enzyme technology was used to synthesize LPGOS, galactooligosaccharides (GOS) that showed to selectively enhance the growth and activity of Lactobacillus plantarum LPLDL®. This was the first time true synergy is demonstrated for a synbiotic in faecal culture.

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